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ea0026oc1.4 | Thyroid/Adrenal | ECE2011

Results of 1,Ortho-1,para′-dichloro-diphenyl-dichloroethane (O,p′DDD) treatment in 76 patients with Cushing's disease

Baudry C , Coste J , Khalil R Bou , Guignat L , Abbas H , Guibourdenche J , Silvera S , Bertagna X , Bertherat J

Introduction: Alternative to transsphenoidal pituitary surgery (TSS) may be required in Cushings disease (CD), as first or second line treatment. 1,ortho-1,para′-dichloro-diphenyl-dichloroethane (o,p′DDD) has a potent anticortisolic action. Its place in CD treatment is not well defined. The aim of this study was to further evaluate the efficacy and tolerance of o,p′DDD in CD.Patients and m...

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ea0026p252 | Pituitary | ECE2011

Initial management and complications of Cushing disease (CD): a French multicenter study of 437 patients

Baudry C , Martinie M , Fathallah-Sahnoun M , Gatta-Cherifi B , Khalil R Bou , Guignat L , Gay E , Raverot G , Brue T , Tabarin A , Chabre O , Bertherat J

Introduction: CD is a rare disease. Our aim was to describe demographic and clinical characteristics together with initial management of patients with CD.Patients and methods: A retrospective analysis of 437 CD patients diagnosed between 1996 and 2009, followed in 5 tertiary centers (Bordeaux, Grenoble, Lyon, Marseille, Paris) was performed in the frame of the national program for rare diseases.Results: 347 (80%) were women. Mean a...

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Endocrine Abstracts

Results of 1,Ortho-1,para′-dichloro-diphenyl-dichloroethane (O,p′DDD) treatment in 76 patients with Cushing's disease

Initial management and complications of Cushing disease (CD): a French multicenter study of 437 patients

BiosciAbstracts